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RS ISO 21446: 2019
Infant formula and adult nutritionals — Determination of trans and total (cis+trans) vitamin K1 content — Normal phase HPLC)
Abstract

This document specifies a method for the quantitative determination of trans and total (cis + trans)
vitamin K1 in infant, pediatric and adult nutritionals using normal phase (NP) high-performance
liquid chromatography (HPLC) with post-column reduction and fluorescence detection. The method
demonstrated good linearity over a standard range of ~2 ?g/l to 80 ?g/l trans vitamin K1, and the limit
of quantification (LOQ) was estimated to be 0,4 ?g/l for standards and 0,09 ?g/100 g ready to feed
(RTF) for samples assuming 4 grams of sample are diluted to 10 ml.

General Information

CodeClassificationThemePagesPublisherAvailability
RS ISO 21446: 2019ADOPTED ISO STANDARDSFood technology27First Edition
Sep 2024		Available
Price: RWF 30,000


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